Crespine Gel should in all cases be injected into the joint by an experienced medical practitioner.

The injection of the treatment is mostly conducted by an orthopedic surgeon or a specialist sports physician.

The application is a so called intra-articular injection. The application of a Crespine Gel treatment without an experienced medical practitioner is not possible.

Medical clarifications before the injection

A prerequisite of a Crespine Gel treatment are prior examinations and medical clarifications by a medical practitioner. On the basis of the results of such clarifications, the expert can decide whether the injection of Crespine Gel in each individual case can be considered as a beneficial possibility to treat the osteoarthritis condition.

Diagnoses of earlier conditions of osteoarthritis are perfectly possible in the meantime. The injecting of Crespine Gel is also extremely suitable for treating early stages of the condition.

The earlier osteoarthritis is diagnosed, the greater the success of the treatment to maintain the original natural joint function can be.

Nowadays, it is possible to diagnose so-called pre-osteoarthritis by using near-infrared-spectroscopy (‘NIR’) methods. At this stage there is no joint degeneration. The earlier osteoarthritis is diagnosed, the better joint degeneration can be slowed down. Crespine Gel can also provide its best results in early stages of osteoarthritis.

Frequent diagnosis procedures before the injection

Often, to back up the diagnosis, x-ray images of the affected joint are taken. When the x-ray image reveals changes in the joint-line ,,the cartilage is usually already severely degenerated.

The condition of the joint cartilage and the synovia membrane can usually be determined by an arthroscopic examination. Blood tests or joint fluid tests can also provide information on possible infections or diseases, to exclude for example rheumatoid arthritis or gout.

Any acute inflammation will render it impossible for a degenerated joint to be treated by Crespine Gel at that point in time. The patient will have to wait until the inflammation has abated, bevor the treatment can be conducted.

The Treatment: the application of the Crespine Gel injection


The entire treatment itself will require only a few minutes. The patient may also require an advisory from the treating medical practitioner. This means, that the duration of the treatment depends on individual requirements and should be discussed in advanced with the specialist selected. Crespine Gel is usually applied by an experienced medical practitioner (an orthopedic surgeon or a specialist sports physician) by injection directly into the joint-line of the affected joint. The use of imaging techniques has been shown to be quality promoting.

Joint before the injection. Degenerated cartilage.

Crespine Gel is injected into the joint to protect and regenerate the cartilage.

The medical practitioner inserts the needle into the joint tissue.

The patient is normally immediately fit for daily routine after the intervention.

Transparent view before the injection.

The puncture site is covered with a plaster afterwards.

The injection of Crespine Gel into joint tissue.

Crespine Gel will protect the cartilage from degeneration

After the application of the Crespine Gel injection

Depending on the diagnosis and the location of the osteoarthritis, it can be reasonable to integrate more activity in everyday life as soon as the pain in the joint is begins to be relieved. Immediately after the intervention, no exaggerated exercise or sporting activities should be undertaken.However, normal day-to-day mobility is directly possible.

The cartilage will be encouraged to regenerate after the treatment by restarting mobility with a healthy amount of activity.

  • A strengthening of the ambient joint muscle tissue will effect additional collateral support.
  • Physio-, Ergo- or physical –therapies can also represent additinal countermeasures when the pain relief in the joint is initiated by Crespine Gel and more mobility is attractive to the patient.
  • Healthy nutrition is also an additional factor for the regeneration of the joint tissue.

In any event, the patient should coordinate optional activities after the intervention with his or her specialist medical practitioner.